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Francisella novicida Mutant XWK4 Triggers Robust Inflammasome Activation Favoring Infection

Bacterial infection tendentiously triggers inflammasome activation, whereas the roles of inflammasome activation in host defense against diverse infections remain unclear. Here, we identified that an ASC-dependent inflammasome activation played opposite roles in host defense against Francisella novi...

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Detalles Bibliográficos
Autores principales: Guo, Yu, Mao, Rudi, Xie, Qingqing, Cheng, Xiaojie, Xu, Tao, Wang, Xiaoyuan, Du, Yan, Qi, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637620/
https://www.ncbi.nlm.nih.gov/pubmed/34869331
http://dx.doi.org/10.3389/fcell.2021.743335