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Paclitaxel-induced stress granules increase LINE-1 mRNA stability to promote drug resistance in breast cancer cells

Abnormal expression of long interspersed element-1 (LINE-1) has been implicated in drug resistance, while our previous study showed that chemotherapy drug paclitaxel (PTX) increased LINE-1 level with unknown mechanism. Bioinformatics analysis suggested the regulation of LINE-1 mRNA by drug-induced s...

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Detalles Bibliográficos
Autores principales: Shi, Xiao, Si, Xinxin, Zhang, Ershao, Zang, Ruochen, Yang, Nan, Cheng, He, Zhang, Zhihong, Pan, Beijing, Sun, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637660/
https://www.ncbi.nlm.nih.gov/pubmed/34857678
http://dx.doi.org/10.7555/JBR.35.20210105