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A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography

The peptide α-helix is right-handed when containing amino acids with l-chirality, and left-handed with d-chirality, however mixed chirality peptides generally do not form α-helices unless a helix inducer such as the non-natural residue amino-isobutyric acid is used. Herein we report the first X-ray...

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Detalles Bibliográficos
Autores principales:	Baeriswyl, Stéphane, Personne, Hippolyte, Di Bonaventura, Ivan, Köhler, Thilo, van Delden, Christian, Stocker, Achim, Javor, Sacha, Reymond, Jean-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637766/ https://www.ncbi.nlm.nih.gov/pubmed/34977576 http://dx.doi.org/10.1039/d1cb00124h

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