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Insights into phosphatase-activated chemical defense in a marine sponge holobiont

Marine sponges often contain potent cytotoxic compounds, which in turn evokes the principle question of how marine sponges avoid self-toxicity. In a marine sponge Discodermia calyx, the highly toxic calyculin A is detoxified by the phosphorylation, which is catalyzed by the phosphotransferase CalQ o...

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Detalles Bibliográficos
Autores principales: Jomori, Takahiro, Matsuda, Kenichi, Egami, Yoko, Abe, Ikuro, Takai, Akira, Wakimoto, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637855/
https://www.ncbi.nlm.nih.gov/pubmed/34977575
http://dx.doi.org/10.1039/d1cb00163a

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