Evidence for Quantum Chemical Effects in Receptor-Ligand Binding Between Integrin and Collagen Fragments — A Computational Investigation With an Impact on Tissue Repair, Neurooncolgy and Glycobiology

The collagen-integrin interactions are mediated by the doubly charged Mg(2+) cation. In nature this cation seems to have the optimal binding strength to stabilize this complex. It is essential that the binding is not too weak so that the complex becomes unstable, however, it is also of importance th...

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Detalles Bibliográficos
Autores principales: Eckert, Thomas, von Cosel, Jan, Kamps, Benedict, Siebert, Hans-Christian, Zhang, Ruiyan, Zhang, Ning, Gousias, Konstantinos, Petridis, Athanasios K., Kanakis, Dimitrios, Falahati, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637888/
https://www.ncbi.nlm.nih.gov/pubmed/34869589
http://dx.doi.org/10.3389/fmolb.2021.756701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637888/
https://www.ncbi.nlm.nih.gov/pubmed/34869589
http://dx.doi.org/10.3389/fmolb.2021.756701

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