A silicon-rhodamine chemical-genetic hybrid for far red voltage imaging from defined neurons in brain slice

We describe the design, synthesis, and application of voltage-sensitive silicon rhodamines. Based on the Berkeley Red Sensor of Transmembrane potential, or BeRST, scaffold, the new dyes possess an isomeric molecular wire for improved alignment in the plasma membrane and 2′ carboxylic acids for ready...

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Detalles Bibliográficos
Autores principales: Ortiz, Gloria, Liu, Pei, Deal, Parker E., Nensel, Ashley K., Martinez, Kayli N., Shamardani, Kiarash, Adesnik, Hillel, Miller, Evan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637932/
https://www.ncbi.nlm.nih.gov/pubmed/34977574
http://dx.doi.org/10.1039/d1cb00156f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637932/
https://www.ncbi.nlm.nih.gov/pubmed/34977574
http://dx.doi.org/10.1039/d1cb00156f

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