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Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis

BACKGROUND: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. MATERIALS AND METHODS: Retrospective review of children with benign renal tumors operated between 2006 and...

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Autores principales: Menon, Prema, Rao, Katragadda Lakshmi Narasimha, Nazki, Saalim, Behera, Saswati, Gupta, Kirti, Samujh, Ram, Solanki, Shailesh, Saxena, Akshay, Bansal, Deepak, Trehan, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637978/
https://www.ncbi.nlm.nih.gov/pubmed/34912134
http://dx.doi.org/10.4103/jiaps.JIAPS_214_20
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author Menon, Prema
Rao, Katragadda Lakshmi Narasimha
Nazki, Saalim
Behera, Saswati
Gupta, Kirti
Samujh, Ram
Solanki, Shailesh
Saxena, Akshay
Bansal, Deepak
Trehan, Amita
author_facet Menon, Prema
Rao, Katragadda Lakshmi Narasimha
Nazki, Saalim
Behera, Saswati
Gupta, Kirti
Samujh, Ram
Solanki, Shailesh
Saxena, Akshay
Bansal, Deepak
Trehan, Amita
author_sort Menon, Prema
collection PubMed
description BACKGROUND: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. MATERIALS AND METHODS: Retrospective review of children with benign renal tumors operated between 2006 and 2018 at one center. RESULTS: Twelve patients (M:F ratio 10:2), age range 3 weeks (31-week gestation) to 13 years presented with large palpable renal swelling (n = 12) and hematuria (n = 3). Computed tomography (CT) scan showed features typical of the tumor. Final histopathology (age group [mean]) showed: multilocular cystic nephroma (MLCN) - n = 5 (41.7%), (11–16 months [13.6]); congenital mesoblastic nephroma (CMN) - n = 4 (33.3%) (classic 1, cellular 3) (0.75–5 months [2.125]); mature cystic teratoma - n = 1 (8.3%): (48 months, in a horseshoe kidney), and angiomyolipoma (AML) - n = 2 (16.7%) (144 months [sporadic] and 156 months [tuberous sclerosis]) One patient with cystic teratoma with no calcification on CT scan received pre-operative chemotherapy as fine-needle aspiration cytology (FNAC) reported malignant small blue cell tumor. Nephroureterectomy with Gerota's fascia could be done easily in all without intraoperative complications. Delay in presentation in MLCN and CMN led to increased symptoms and CT scan changes. All patients did well in 1.5–12 years (median 3 years) follow-up including cellular mesoblastic nephroma. CONCLUSIONS: Benign renal tumors often occur in specific age groups but may overlap that of Wilms tumor. Proper interpretation of clinical presentation, CT scan, and FNAC findings help in avoiding preoperative chemotherapy. Upfront nephroureterectomy is curative. Histopathological findings decide further treatment. Children with AML and tuberous sclerosis need lifelong follow-up.
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spelling pubmed-86379782021-12-14 Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis Menon, Prema Rao, Katragadda Lakshmi Narasimha Nazki, Saalim Behera, Saswati Gupta, Kirti Samujh, Ram Solanki, Shailesh Saxena, Akshay Bansal, Deepak Trehan, Amita J Indian Assoc Pediatr Surg Original Article BACKGROUND: Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature. MATERIALS AND METHODS: Retrospective review of children with benign renal tumors operated between 2006 and 2018 at one center. RESULTS: Twelve patients (M:F ratio 10:2), age range 3 weeks (31-week gestation) to 13 years presented with large palpable renal swelling (n = 12) and hematuria (n = 3). Computed tomography (CT) scan showed features typical of the tumor. Final histopathology (age group [mean]) showed: multilocular cystic nephroma (MLCN) - n = 5 (41.7%), (11–16 months [13.6]); congenital mesoblastic nephroma (CMN) - n = 4 (33.3%) (classic 1, cellular 3) (0.75–5 months [2.125]); mature cystic teratoma - n = 1 (8.3%): (48 months, in a horseshoe kidney), and angiomyolipoma (AML) - n = 2 (16.7%) (144 months [sporadic] and 156 months [tuberous sclerosis]) One patient with cystic teratoma with no calcification on CT scan received pre-operative chemotherapy as fine-needle aspiration cytology (FNAC) reported malignant small blue cell tumor. Nephroureterectomy with Gerota's fascia could be done easily in all without intraoperative complications. Delay in presentation in MLCN and CMN led to increased symptoms and CT scan changes. All patients did well in 1.5–12 years (median 3 years) follow-up including cellular mesoblastic nephroma. CONCLUSIONS: Benign renal tumors often occur in specific age groups but may overlap that of Wilms tumor. Proper interpretation of clinical presentation, CT scan, and FNAC findings help in avoiding preoperative chemotherapy. Upfront nephroureterectomy is curative. Histopathological findings decide further treatment. Children with AML and tuberous sclerosis need lifelong follow-up. Wolters Kluwer - Medknow 2021 2021-11-12 /pmc/articles/PMC8637978/ /pubmed/34912134 http://dx.doi.org/10.4103/jiaps.JIAPS_214_20 Text en Copyright: © 2021 Journal of Indian Association of Pediatric Surgeons https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Menon, Prema
Rao, Katragadda Lakshmi Narasimha
Nazki, Saalim
Behera, Saswati
Gupta, Kirti
Samujh, Ram
Solanki, Shailesh
Saxena, Akshay
Bansal, Deepak
Trehan, Amita
Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title_full Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title_fullStr Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title_full_unstemmed Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title_short Benign Renal Tumors in Pediatric Age Group: Retrospective Analysis
title_sort benign renal tumors in pediatric age group: retrospective analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637978/
https://www.ncbi.nlm.nih.gov/pubmed/34912134
http://dx.doi.org/10.4103/jiaps.JIAPS_214_20
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