Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer’s disease

BACKGROUND: Growing evidence indicates that inflammasome-mediated inflammation plays important roles in the pathophysiology of amnestic mild cognitive impairment (aMCI) and Alzheimer’s disease (AD). Pyroptosis induced by inflammasome, and Gasdermin D (GSDMD) is involved in several neurodegenerative...

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Detalles Bibliográficos
Autores principales: Rui, Wenjuan, Xiao, Hong, Fan, Yi, Ma, Zhongxuan, Xiao, Ming, Li, Sheng, Shi, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638109/
https://www.ncbi.nlm.nih.gov/pubmed/34856990
http://dx.doi.org/10.1186/s12974-021-02329-2

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