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Gallium-68 Labeling of the Cyclin-Dependent Kinase 4/6 Inhibitors as Positron Emission Tomography Radiotracers for Tumor Imaging

[Image: see text] Cyclin-dependent kinase 4 and 6 (CDK4/6) have emerged as interesting therapeutic drug targets with many potential applications in anti-tumors, especially in breast cancer. A novel CDK4/6 kinase-derived positron emission tomography (PET) imaging agent was designed based on palbocicl...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Yang, Ziyi, Liu, Mingyu, Wang, Xiangwei, Song, Shaoli, Xu, Xiaoping, Yang, Zhongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638300/
https://www.ncbi.nlm.nih.gov/pubmed/34870045
http://dx.doi.org/10.1021/acsomega.1c05073