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Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study

BACKGROUND: Muscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults. MET...

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Autores principales: Kim, Hyunkyu, Kim, Seung Hoon, Jeong, Wonjeong, Jang, Sung-In, Park, Eun-Cheol, Kim, Youseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638365/
https://www.ncbi.nlm.nih.gov/pubmed/34852792
http://dx.doi.org/10.1186/s12877-021-02610-2
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author Kim, Hyunkyu
Kim, Seung Hoon
Jeong, Wonjeong
Jang, Sung-In
Park, Eun-Cheol
Kim, Youseok
author_facet Kim, Hyunkyu
Kim, Seung Hoon
Jeong, Wonjeong
Jang, Sung-In
Park, Eun-Cheol
Kim, Youseok
author_sort Kim, Hyunkyu
collection PubMed
description BACKGROUND: Muscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults. METHODS: Our study used data from the Korean Longitudinal Study of Aging (KLoSA). The analysis covered 6696 participants who had taken the handgrip strength test and Mini-Mental State Examination (MMSE) from 2006 to 2018. We adopted general estimating equations to assess the temporal effect of handgrip strength change on cognitive function. RESULTS: After adjusting for covariates, we observed an association between handgrip strength and low MMSE scores (β = − 0.3142 in men, β = − 0.2685 in women). Handgrip strength as a continuous variable was positively correlated with MMSE scores after adjustment (β = 0.0293 in men, β = 0.0347 in women). The group with decreased handgrip strength over time also showed greater odds for mild cognitive impairment (OR = 1.23, 95%CI = 1.05–1.27 in men, OR = 1.15, 95%CI = 1.05–1.27 in women) and dementia (OR = 1.393, 95%CI = 1.18–1.65 in men, OR = 1.19, 95%CI = 1.08–1.32 in women). CONCLUSIONS: This study identified the relationship between handgrip strength change and cognitive function among South Korean adults. According to our large, longitudinal sample, decreasing handgrip strength was associated with decline in cognitive function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02610-2.
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spelling pubmed-86383652021-12-03 Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study Kim, Hyunkyu Kim, Seung Hoon Jeong, Wonjeong Jang, Sung-In Park, Eun-Cheol Kim, Youseok BMC Geriatr Research BACKGROUND: Muscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults. METHODS: Our study used data from the Korean Longitudinal Study of Aging (KLoSA). The analysis covered 6696 participants who had taken the handgrip strength test and Mini-Mental State Examination (MMSE) from 2006 to 2018. We adopted general estimating equations to assess the temporal effect of handgrip strength change on cognitive function. RESULTS: After adjusting for covariates, we observed an association between handgrip strength and low MMSE scores (β = − 0.3142 in men, β = − 0.2685 in women). Handgrip strength as a continuous variable was positively correlated with MMSE scores after adjustment (β = 0.0293 in men, β = 0.0347 in women). The group with decreased handgrip strength over time also showed greater odds for mild cognitive impairment (OR = 1.23, 95%CI = 1.05–1.27 in men, OR = 1.15, 95%CI = 1.05–1.27 in women) and dementia (OR = 1.393, 95%CI = 1.18–1.65 in men, OR = 1.19, 95%CI = 1.08–1.32 in women). CONCLUSIONS: This study identified the relationship between handgrip strength change and cognitive function among South Korean adults. According to our large, longitudinal sample, decreasing handgrip strength was associated with decline in cognitive function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02610-2. BioMed Central 2021-12-01 /pmc/articles/PMC8638365/ /pubmed/34852792 http://dx.doi.org/10.1186/s12877-021-02610-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kim, Hyunkyu
Kim, Seung Hoon
Jeong, Wonjeong
Jang, Sung-In
Park, Eun-Cheol
Kim, Youseok
Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title_full Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title_fullStr Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title_full_unstemmed Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title_short Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study
title_sort association between change in handgrip strength and cognitive function in korean adults: a longitudinal panel study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638365/
https://www.ncbi.nlm.nih.gov/pubmed/34852792
http://dx.doi.org/10.1186/s12877-021-02610-2
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