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A nuanced role of the small loop of hepatitis B virus small envelope protein in virion morphogenesis and secretion
BACKGROUND: The virion secretion mechanism of human hepatitis B virus (HBV) remains to be investigated. In our current study, we characterized a reverse transcriptase mutant, which changed from the YMDD motif to YMHA. We noted that this mutant YMHA secreted no virions in the medium. Because of the o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638367/ https://www.ncbi.nlm.nih.gov/pubmed/34852809 http://dx.doi.org/10.1186/s12929-021-00780-0 |