Cargando…

Psilocybin-assisted therapy for the treatment of resistant major depressive disorder (PsiDeR): protocol for a randomised, placebo-controlled feasibility trial

INTRODUCTION: Psilocybin-assisted therapy may be a new treatment for major depressive disorder (MDD), with encouraging data from pilot trials. In this trial (short name: PsiDeR) we aimed to test the feasibility of a parallel-group, randomised, placebo-controlled design. The primary outcomes in this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rucker, James, Jafari, Hassan, Mantingh, Tim, Bird, Catherine, Modlin, Nadav Liam, Knight, Gemma, Reinholdt, Frederick, Day, Camilla, Carter, Ben, Young, Allan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Mental Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638462/ https://www.ncbi.nlm.nih.gov/pubmed/34853114 http://dx.doi.org/10.1136/bmjopen-2021-056091

Ejemplares similares

Psilocybin: From Serendipity to Credibility?
por: Rucker, James J., et al.
Publicado: (2021)

The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation
por: Rucker, James J, et al.
Publicado: (2022)

Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial (The QUANTUM Trip Trial)
por: Jensen, Mathias Ebbesen, et al.
Publicado: (2022)

Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study
por: Cavanna, Federico, et al.
Publicado: (2022)

Development and Evaluation of a Therapist Training Program for Psilocybin Therapy for Treatment-Resistant Depression in Clinical Research
por: Tai, Sara J., et al.
Publicado: (2021)

Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020
por: Kopra, Emma I, et al.
Publicado: (2023)

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
por: Carhart-Harris, R. L., et al.
Publicado: (2017)

The Therapeutic Potential of Psilocybin
por: Lowe, Henry, et al.
Publicado: (2021)

Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial
por: Deb, Shoumitro, et al.
Publicado: (2020)

Homebrewed psilocybin: can new routes for pharmaceutical psilocybin production enable recreational use?
por: Gibbons, William J., et al.
Publicado: (2021)

Individual patient data meta-analysis of combined treatments versus psychotherapy (with or without pill placebo), pharmacotherapy or pill placebo for adult depression: a protocol
por: Weitz, Erica, et al.
Publicado: (2017)

Placebo effects in mental health disorders: protocol for an umbrella review
por: Huneke, Nathan TM, et al.
Publicado: (2023)

PLAN-e-PSY, a mobile application to improve case management and patient’s functioning in first episode psychosis: protocol for an open-label, multicentre, superiority, randomised controlled trial
por: Haesebaert, Frédéric, et al.
Publicado: (2021)

Psilocybin: the magic medicine for depression?
por: Corrigan, Amber Elyse, et al.
Publicado: (2021)

Electrical spiking of psilocybin fungi
por: Gandia, Antoni, et al.
Publicado: (2022)

Psilocybin in Palliative Care: An Update
por: Whinkin, Emily, et al.
Publicado: (2023)

Psilocybin desynchronizes brain networks
por: Siegel, Joshua S, et al.
Publicado: (2023)

Psilocybin for Depression: From Credibility to Feasibility, What’s Missing?
por: Munafò, Antonio, et al.
Publicado: (2022)

Prevention of psychosocial distress consequences in somatic hospital inpatients via a stepped and collaborative care model: protocol of SomPsyNet, a stepped wedge cluster randomised trial
por: Meinlschmidt, Gunther, et al.
Publicado: (2023)

Short-term oestrogen as a strategy to prevent postpartum depression in high-risk women: protocol for the double-blind, randomised, placebo-controlled MAMA clinical trial
por: Høgh, Stinne, et al.
Publicado: (2021)

Impact of placebo arms on outcomes in antidepressant trials: systematic review and meta-regression analysis
por: Salanti, Georgia, et al.
Publicado: (2018)

Depression, Mindfulness, and Psilocybin: Possible Complementary Effects of Mindfulness Meditation and Psilocybin in the Treatment of Depression. A Review
por: Heuschkel, Kristin, et al.
Publicado: (2020)

Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study in Healthy Subjects
por: Becker, Anna M., et al.
Publicado: (2021)

Prediction of Psilocybin Response in Healthy Volunteers
por: Studerus, Erich, et al.
Publicado: (2012)

Effects of psilocybin therapy on personality structure
por: Erritzoe, D., et al.
Publicado: (2018)

Rediscovering Psilocybin as an Antidepressive Treatment Strategy
por: Zeiss, Rene, et al.
Publicado: (2021)

Policy in focus: Is psilocybin the next cannabis?
por: Basky, Greg
Publicado: (2021)

Unraveling the Mysteries of Mental Illness With Psilocybin
por: Sottile, Robert, et al.
Publicado: (2022)

Psychotherapy with Psilocybin for Depression: Systematic Review
por: Dawood Hristova, Jonathan Joseph, et al.
Publicado: (2023)

Open-label placebo for insomnia (OPIN): study protocol for a cohort multiple randomised controlled trial
por: Colagiuri, Ben, et al.
Publicado: (2021)

Citalopram for major depressive disorder in adults: a systematic review and meta-analysis of published placebo-controlled trials
por: Apler, Alex
Publicado: (2011)

Individual placement and support (IPS) for patients with offending histories: the IPSOH feasibility cluster randomised trial protocol
por: Khalifa, N, et al.
Publicado: (2016)

Protocol for a systematic review and meta-analysis of the placebo response in treatment-resistant depression: comparison of multiple treatment modalities
por: Jones, Brett D M, et al.
Publicado: (2021)

Efficacy and acceptability of adjunctive psychological and pharmacological interventions for treatment-resistant depression: protocol for a systematic review and network meta-analysis
por: Husain, Muhammad Ishrat, et al.
Publicado: (2019)

Combining cognitive bias modification training (CBM) and transcranial direct current stimulation (tDCS) to treat binge eating disorder: study protocol of a randomised controlled feasibility trial
por: Gordon, Gemma, et al.
Publicado: (2019)

MAGDALENA: study protocol of a randomised, placebo-controlled trial on cognitive development at 2 years of age in children exposed to SSRI in utero
por: Heinonen, Essi, et al.
Publicado: (2018)

The effect of intranasal oxytocin on the perception of affective touch and multisensory integration in anorexia nervosa: protocol for a double-blind placebo-controlled crossover study
por: Crucianelli, Laura, et al.
Publicado: (2019)

Effect of Psilocybin on Empathy and Moral Decision-Making
por: Pokorny, Thomas, et al.
Publicado: (2017)

Psilocybin and Mental Health–Don't Lose Control
por: Barnby, Joseph M., et al.
Publicado: (2018)

Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin
por: Fricke, Janis, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g856tuea8cspumml59ov9oert4