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Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis

The NLRP3 (NLR [NOD-like receptor] family, pyrin domain containing 3) inflammasome is an important driver of atherosclerosis. Our previous study shows that chaperone-mediated autophagy (CMA), one of the main lysosomal degradative process, has a regulatory role in lipid metabolism of macrophages. How...

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Detalles Bibliográficos
Autores principales: Qiao, Lei, Ma, Jing, Zhang, Zihao, Sui, Wenhai, Zhai, Chungang, Xu, Dan, Wang, Zunzhe, Lu, Huixia, Zhang, Meng, Zhang, Cheng, Chen, Wenqiang, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638823/
https://www.ncbi.nlm.nih.gov/pubmed/34704457
http://dx.doi.org/10.1161/CIRCRESAHA.121.318908