Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals

Expression QTL (eQTL) analyses have suggested many genes mediating genome-wide association study (GWAS) signals but most GWAS signals still lack compelling explanatory genes. We have leveraged an adipose-specific gene regulatory network to infer expression regulator activities and phenotypic master...

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Detalles Bibliográficos
Autores principales: Hoskins, Jason W., Chung, Charles C., O’Brien, Aidan, Zhong, Jun, Connelly, Katelyn, Collins, Irene, Shi, Jianxin, Amundadottir, Laufey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639061/
https://www.ncbi.nlm.nih.gov/pubmed/34793442
http://dx.doi.org/10.1371/journal.pcbi.1009563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639061/
https://www.ncbi.nlm.nih.gov/pubmed/34793442
http://dx.doi.org/10.1371/journal.pcbi.1009563

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