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Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study

PURPOSE: To determine the prevalence and clinical presentation of participants with glaucoma attending a public eye care facility in Nigeria. METHOD: Hospital based retrospective study of glaucoma participants aged 50 years and above seen over a 5-year period. Descriptive statistics summarized the d...

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Autores principales: Ezinne, Ngozika E., Ojukwu, Chukwuebuka S., Ekemiri, Kingsley K., Akano, Obinna F., Ekure, Edgar, Osuagwu, Uchechukwu Levi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639068/
https://www.ncbi.nlm.nih.gov/pubmed/34855905
http://dx.doi.org/10.1371/journal.pone.0260965
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author Ezinne, Ngozika E.
Ojukwu, Chukwuebuka S.
Ekemiri, Kingsley K.
Akano, Obinna F.
Ekure, Edgar
Osuagwu, Uchechukwu Levi
author_facet Ezinne, Ngozika E.
Ojukwu, Chukwuebuka S.
Ekemiri, Kingsley K.
Akano, Obinna F.
Ekure, Edgar
Osuagwu, Uchechukwu Levi
author_sort Ezinne, Ngozika E.
collection PubMed
description PURPOSE: To determine the prevalence and clinical presentation of participants with glaucoma attending a public eye care facility in Nigeria. METHOD: Hospital based retrospective study of glaucoma participants aged 50 years and above seen over a 5-year period. Descriptive statistics summarized the demographic, clinical characteristics and treatment of the participants and determined the association of variables with gender and age. Prevalence of the glaucoma by type, and their 95% confidence intervals (CI) were also calculated. RESULT: Of the 5482 case files that were reviewed, 995 (18.15%, 95% Cl 17.15–19.19%) had glaucoma particularly primary open angle glaucoma (11.55%, 95%CI 10.73–12.42%) and were mostly females (564, 56.7%) aged 69 ± 12 years (range, 50–103 years). In contrast to other glaucoma types, the prevalence of primary angle closure glaucoma (3.68, 95%CI 3.22–4.22) increased by 15% over 5 years. The mean intraocular pressure ranged from 15–50 mmHg but higher in females than males (27.8 ± 6.1mmHg versus 26.6 ± 6.0 mmHg, P <0.05) who had comparable VA (0.58 ± 0.4 Log MAR) and cup-disc ratios (P >0.05). On presentation, the glaucoma hemi field test (GHFT) was outside the normal limits in 45.5% and 54.5% of males and females, respectively. The type of visual field defect was associated with glaucoma type (P = 0.047). Arcuate scotoma was most common (35.5%) across glaucoma types, paracentral scotoma more common in Secondary glaucoma while Seidel scotoma was highest in NTG (19.3%). Beta-blocker was the mainstay of management (42.2%) but more likely to be prescribed to males while more females received carbonic anhydrase inhibitors. CONCLUSIONS: The high prevalence of glaucoma in older people remains a public health problem in Nigeria. The fact that about half of the participants presented with visual field defect suggests there is a need for public health messages to emphasize on early glaucoma screening, detection and management.
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spelling pubmed-86390682021-12-03 Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study Ezinne, Ngozika E. Ojukwu, Chukwuebuka S. Ekemiri, Kingsley K. Akano, Obinna F. Ekure, Edgar Osuagwu, Uchechukwu Levi PLoS One Research Article PURPOSE: To determine the prevalence and clinical presentation of participants with glaucoma attending a public eye care facility in Nigeria. METHOD: Hospital based retrospective study of glaucoma participants aged 50 years and above seen over a 5-year period. Descriptive statistics summarized the demographic, clinical characteristics and treatment of the participants and determined the association of variables with gender and age. Prevalence of the glaucoma by type, and their 95% confidence intervals (CI) were also calculated. RESULT: Of the 5482 case files that were reviewed, 995 (18.15%, 95% Cl 17.15–19.19%) had glaucoma particularly primary open angle glaucoma (11.55%, 95%CI 10.73–12.42%) and were mostly females (564, 56.7%) aged 69 ± 12 years (range, 50–103 years). In contrast to other glaucoma types, the prevalence of primary angle closure glaucoma (3.68, 95%CI 3.22–4.22) increased by 15% over 5 years. The mean intraocular pressure ranged from 15–50 mmHg but higher in females than males (27.8 ± 6.1mmHg versus 26.6 ± 6.0 mmHg, P <0.05) who had comparable VA (0.58 ± 0.4 Log MAR) and cup-disc ratios (P >0.05). On presentation, the glaucoma hemi field test (GHFT) was outside the normal limits in 45.5% and 54.5% of males and females, respectively. The type of visual field defect was associated with glaucoma type (P = 0.047). Arcuate scotoma was most common (35.5%) across glaucoma types, paracentral scotoma more common in Secondary glaucoma while Seidel scotoma was highest in NTG (19.3%). Beta-blocker was the mainstay of management (42.2%) but more likely to be prescribed to males while more females received carbonic anhydrase inhibitors. CONCLUSIONS: The high prevalence of glaucoma in older people remains a public health problem in Nigeria. The fact that about half of the participants presented with visual field defect suggests there is a need for public health messages to emphasize on early glaucoma screening, detection and management. Public Library of Science 2021-12-02 /pmc/articles/PMC8639068/ /pubmed/34855905 http://dx.doi.org/10.1371/journal.pone.0260965 Text en © 2021 Ezinne et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ezinne, Ngozika E.
Ojukwu, Chukwuebuka S.
Ekemiri, Kingsley K.
Akano, Obinna F.
Ekure, Edgar
Osuagwu, Uchechukwu Levi
Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title_full Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title_fullStr Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title_full_unstemmed Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title_short Prevalence and clinical profile of glaucoma patients in rural Nigeria—A hospital based study
title_sort prevalence and clinical profile of glaucoma patients in rural nigeria—a hospital based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639068/
https://www.ncbi.nlm.nih.gov/pubmed/34855905
http://dx.doi.org/10.1371/journal.pone.0260965
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