A Phase 2a randomized, single-center, double-blind, placebo-controlled study to evaluate the safety and preliminary efficacy of oral iOWH032 against cholera diarrhea in a controlled human infection model

Cholera remains a major cause of infectious diarrhea globally. Despite the increased availability of cholera vaccines, there is still an urgent need for other effective interventions to reduce morbidity and mortality. Furthermore, increased prevalence of antibiotic-resistant Vibrio cholerae threaten...

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Detalles Bibliográficos
Autores principales: Erdem, Rahsan, Ambler, Gwen, Al-Ibrahim, Mohamed, Fraczek, Katarzyna, Dong, Steven D., Gast, Christopher, Mercer, Laina D., Raine, Michael, Tennant, Sharon M., Chen, Wilbur H., de Hostos, Eugenio L., Choy, Robert K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639072/
https://www.ncbi.nlm.nih.gov/pubmed/34793441
http://dx.doi.org/10.1371/journal.pntd.0009969

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