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Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B.1.1.7), Beta (B.1.351) and Delta variant (B.1.617.2)
SARS-CoV-2 variants are emerging with potential increased transmissibility highlighting the great unmet medical need for new therapies. Niclosamide is a potent anti-SARS-CoV-2 agent that has advanced in clinical development. We validate the potent antiviral efficacy of niclosamide in a SARS-CoV-2 hu...
Autores principales: | Weiss, Anne, Touret, Franck, Baronti, Cecile, Gilles, Magali, Hoen, Bruno, Nougairède, Antoine, de Lamballerie, Xavier, Sommer, Morten O. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639074/ https://www.ncbi.nlm.nih.gov/pubmed/34855904 http://dx.doi.org/10.1371/journal.pone.0260958 |
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