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Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test

OBJECTIVE: The latent tuberculosis infection (LTBI) is a state of persistent immune response to stimulation by Mycobacterium Tuberculosis antigens without clinical manifestation: the healthcare workers (HCWs) have a higher exposure risk so prevention is an important challenge for occupational medici...

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Autores principales: COPPETA, LUCA, FERRARI, CRISTIANA, FERRARO, MARIACARMELA, BALDI, SAVINO, GRANDE, STEFANIA, DE ZORDO, LUDOVICO MARIA, MATTONE, PIER FRANCESCO, DODDATO, MARIA TERESA, BALBI, OTTAVIA, MAGRINI, ANDREA, PIETROIUSTI, ANTONIO, LIETO, PIERGIORGIO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639116/
https://www.ncbi.nlm.nih.gov/pubmed/34909505
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.3.1471
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author COPPETA, LUCA
FERRARI, CRISTIANA
FERRARO, MARIACARMELA
BALDI, SAVINO
GRANDE, STEFANIA
DE ZORDO, LUDOVICO MARIA
MATTONE, PIER FRANCESCO
DODDATO, MARIA TERESA
BALBI, OTTAVIA
MAGRINI, ANDREA
PIETROIUSTI, ANTONIO
LIETO, PIERGIORGIO
author_facet COPPETA, LUCA
FERRARI, CRISTIANA
FERRARO, MARIACARMELA
BALDI, SAVINO
GRANDE, STEFANIA
DE ZORDO, LUDOVICO MARIA
MATTONE, PIER FRANCESCO
DODDATO, MARIA TERESA
BALBI, OTTAVIA
MAGRINI, ANDREA
PIETROIUSTI, ANTONIO
LIETO, PIERGIORGIO
author_sort COPPETA, LUCA
collection PubMed
description OBJECTIVE: The latent tuberculosis infection (LTBI) is a state of persistent immune response to stimulation by Mycobacterium Tuberculosis antigens without clinical manifestation: the healthcare workers (HCWs) have a higher exposure risk so prevention is an important challenge for occupational medicine. The aim of our study is to evaluate the prevalence of LTBI among HCWs of the Foundation Policlinic “Tor Vergata”. METHODS: This is a retrospective study conducted by analyzing the clinical records of 825 HCWs of the PTV, from January 1st to December 31th 2016. To evaluate the TB infection we used the Quantiferon TB Gold interferon-gamma release assay. RESULTS: Our study underlines the low prevalence of LTBI in the Italian healthcare workers. CONCLUSION: Although the LTBI status is not contagious, the diagnosis and the safety strategies require specific clinical and preventive considerations.
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spelling pubmed-86391162021-12-13 Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test COPPETA, LUCA FERRARI, CRISTIANA FERRARO, MARIACARMELA BALDI, SAVINO GRANDE, STEFANIA DE ZORDO, LUDOVICO MARIA MATTONE, PIER FRANCESCO DODDATO, MARIA TERESA BALBI, OTTAVIA MAGRINI, ANDREA PIETROIUSTI, ANTONIO LIETO, PIERGIORGIO J Prev Med Hyg Research Article OBJECTIVE: The latent tuberculosis infection (LTBI) is a state of persistent immune response to stimulation by Mycobacterium Tuberculosis antigens without clinical manifestation: the healthcare workers (HCWs) have a higher exposure risk so prevention is an important challenge for occupational medicine. The aim of our study is to evaluate the prevalence of LTBI among HCWs of the Foundation Policlinic “Tor Vergata”. METHODS: This is a retrospective study conducted by analyzing the clinical records of 825 HCWs of the PTV, from January 1st to December 31th 2016. To evaluate the TB infection we used the Quantiferon TB Gold interferon-gamma release assay. RESULTS: Our study underlines the low prevalence of LTBI in the Italian healthcare workers. CONCLUSION: Although the LTBI status is not contagious, the diagnosis and the safety strategies require specific clinical and preventive considerations. Pacini Editore Srl 2021-09-15 /pmc/articles/PMC8639116/ /pubmed/34909505 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.3.1471 Text en ©2021 Pacini Editore SRL, Pisa, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Research Article
COPPETA, LUCA
FERRARI, CRISTIANA
FERRARO, MARIACARMELA
BALDI, SAVINO
GRANDE, STEFANIA
DE ZORDO, LUDOVICO MARIA
MATTONE, PIER FRANCESCO
DODDATO, MARIA TERESA
BALBI, OTTAVIA
MAGRINI, ANDREA
PIETROIUSTI, ANTONIO
LIETO, PIERGIORGIO
Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title_full Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title_fullStr Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title_full_unstemmed Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title_short Risk of latent tuberculosis infection among healthcare workers in Italy: a retrospective study with Quantiferon Test
title_sort risk of latent tuberculosis infection among healthcare workers in italy: a retrospective study with quantiferon test
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639116/
https://www.ncbi.nlm.nih.gov/pubmed/34909505
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.3.1471
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