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Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)

Acute lymphoblastic leukemia (ALL) is a neoplasm of the B cell or T cell. Diagnosis is made by peripheral blood smear and bone marrow biopsy. Those with relapse/measurable residual disease (MRD) present with fever, weakness, fatigue, and easy bruising due to bone marrow infiltration (Kantarjian et a...

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Detalles Bibliográficos
Autores principales: Maslov, Diana V., Badari, Ambuga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639275/
https://www.ncbi.nlm.nih.gov/pubmed/34868692
http://dx.doi.org/10.1155/2021/9953230
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author Maslov, Diana V.
Badari, Ambuga
author_facet Maslov, Diana V.
Badari, Ambuga
author_sort Maslov, Diana V.
collection PubMed
description Acute lymphoblastic leukemia (ALL) is a neoplasm of the B cell or T cell. Diagnosis is made by peripheral blood smear and bone marrow biopsy. Those with relapse/measurable residual disease (MRD) present with fever, weakness, fatigue, and easy bruising due to bone marrow infiltration (Kantarjian et al., 2017). A 59-year-old male with history of relapsed acute lymphoblastic leukemia and allogeneic stem cell transplant presented to the Emergency Department (ED) multiple times with shortness of breath. 2D Echo revealed recurrent pericardial effusion. His MRD was discovered in the pericardium. He underwent the creation of a pericardial window with cytology and culture which confirmed B cell lymphoblastic leukemia/lymphoma, consistent with relapsed disease. We present a case of a patient with B-ALL and MRD who presented with symptoms of shortness of breath. His MRD was discovered not in the bone marrow, but in the pericardium.
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spelling pubmed-86392752021-12-03 Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL) Maslov, Diana V. Badari, Ambuga Case Rep Oncol Med Case Report Acute lymphoblastic leukemia (ALL) is a neoplasm of the B cell or T cell. Diagnosis is made by peripheral blood smear and bone marrow biopsy. Those with relapse/measurable residual disease (MRD) present with fever, weakness, fatigue, and easy bruising due to bone marrow infiltration (Kantarjian et al., 2017). A 59-year-old male with history of relapsed acute lymphoblastic leukemia and allogeneic stem cell transplant presented to the Emergency Department (ED) multiple times with shortness of breath. 2D Echo revealed recurrent pericardial effusion. His MRD was discovered in the pericardium. He underwent the creation of a pericardial window with cytology and culture which confirmed B cell lymphoblastic leukemia/lymphoma, consistent with relapsed disease. We present a case of a patient with B-ALL and MRD who presented with symptoms of shortness of breath. His MRD was discovered not in the bone marrow, but in the pericardium. Hindawi 2021-11-25 /pmc/articles/PMC8639275/ /pubmed/34868692 http://dx.doi.org/10.1155/2021/9953230 Text en Copyright © 2021 Diana V. Maslov and Ambuga Badari. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Maslov, Diana V.
Badari, Ambuga
Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title_full Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title_fullStr Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title_full_unstemmed Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title_short Pericardial Relapse of Acute Lymphoblastic Leukemia (ALL)
title_sort pericardial relapse of acute lymphoblastic leukemia (all)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639275/
https://www.ncbi.nlm.nih.gov/pubmed/34868692
http://dx.doi.org/10.1155/2021/9953230
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