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Distant residues modulate conformational opening in SARS-CoV-2 spike protein

Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) involves the attachment of the receptor-binding domain (RBD) of its spike proteins to the ACE2 receptors on the peripheral membrane of host cells. Binding is initiated by a down-to-up conformational change in the spike protein...

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Detalles Bibliográficos
Autores principales: Ray, Dhiman, Le, Ly, Andricioaei, Ioan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639331/
https://www.ncbi.nlm.nih.gov/pubmed/34615730
http://dx.doi.org/10.1073/pnas.2100943118