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Distant residues modulate conformational opening in SARS-CoV-2 spike protein
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) involves the attachment of the receptor-binding domain (RBD) of its spike proteins to the ACE2 receptors on the peripheral membrane of host cells. Binding is initiated by a down-to-up conformational change in the spike protein...
Autores principales: | Ray, Dhiman, Le, Ly, Andricioaei, Ioan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639331/ https://www.ncbi.nlm.nih.gov/pubmed/34615730 http://dx.doi.org/10.1073/pnas.2100943118 |
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