Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway

T cell antigen receptor (TCR) and B cell antigen receptor (BCR) signaling are initiated and tightly regulated by Src-family kinases (SFKs). SFKs positively regulate TCR signaling in naïve T cells but have both positive and negative regulatory roles in BCR signaling in naïve B cells. The proper regul...

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Detalles Bibliográficos
Autores principales: Lu, Wen, Skrzypczynska, Katarzyna M., Weiss, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639343/
https://www.ncbi.nlm.nih.gov/pubmed/34675079
http://dx.doi.org/10.1073/pnas.2108957118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639343/
https://www.ncbi.nlm.nih.gov/pubmed/34675079
http://dx.doi.org/10.1073/pnas.2108957118

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