Cargando…

Dual-targeted carbon-dot-drugs nanoassemblies for modulating Alzheimer's related amyloid-β aggregation and inhibiting fungal infection

Amyloid aggregation and fungal infection, especially amyloid beta (Aβ) peptide and Candida albicans are considered as two of the crucial pathogenic agents in Alzheimer's disease (AD). In this work, we propose an innovative treatment strategy for AD, targeting at not only Aβ aggregation but also...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Chaoren, Wang, Chaoli, Shao, Xu, Shu, Qi, Hu, Xiaoling, Guan, Ping, Teng, Yonggang, Cheng, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639470/ https://www.ncbi.nlm.nih.gov/pubmed/34901820 http://dx.doi.org/10.1016/j.mtbio.2021.100167

Ejemplares similares

Advanced nanomaterials for modulating Alzheimer's related amyloid aggregation
por: Shao, Xu, et al.
Publicado: (2022)

Hybrid Amyloid Quantum Dot Nanoassemblies to Probe Neuroinflammatory Damage
por: Chiang, Wesley, et al.
Publicado: (2023)

Carbon dots conjugated to SN38 for improved colorectal anticancer therapy
por: Mattinzoli, Deborah, et al.
Publicado: (2022)

Inheritance of physico-chemical properties and ROS generation by carbon quantum dots derived from pyrolytically carbonized bacterial sources
por: Wu, Y., et al.
Publicado: (2021)

Developing a Fluorescent Hybrid Nanobiosensor Based on Quantum Dots and Azoreductase Enzyme for Methyl Red Monitoring
por: Hajipour, Fahimeh, et al.
Publicado: (2021)

Intrinsic specificity of plain ammonium citrate carbon dots for Helicobacter pylori: Interfacial mechanism, diagnostic translation and general revelation
por: Geng, Jiayue, et al.
Publicado: (2022)

On the plasticity of amyloid formation: The impact of destabilizing small to large substitutions on islet amyloid polypeptide amyloid formation
por: Manathunga, Lakshan, et al.
Publicado: (2023)

E674Q (Shanghai APP mutant), a novel amyloid precursor protein mutation, in familial late-onset Alzheimer's disease
por: Zhang, Yongfang, et al.
Publicado: (2023)

Activation of a passive, mesoporous silica nanoparticle layer through attachment of bacterially-derived carbon-quantum-dots for protection and functional enhancement of probiotics
por: Wei, Hao, et al.
Publicado: (2022)

Suppression of a core metabolic enzyme dihydrolipoamide dehydrogenase (dld) protects against amyloid beta toxicity in C. elegans model of Alzheimer's disease
por: Ahmad, Waqar, et al.
Publicado: (2020)

Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was beneficial for long-term treatment of osteoarthritis
por: Yin, Zhaowei, et al.
Publicado: (2023)

Identification and Evaluation of Novel Drug Targets against the Human Fungal Pathogen Aspergillus fumigatus with Elaboration on the Possible Role of RNA-Binding Protein
por: Malekzadeh, Saeid, et al.
Publicado: (2017)

Secretome of Aggregated Embryonic Stem Cell-Derived Mesenchymal Stem Cell Modulates the Release of Inflammatory Factors in Lipopolysaccharide-Induced Peripheral Blood Mononuclear Cells
por: Ghahhari, Nastaran Mohammadi, et al.
Publicado: (2018)

Carvacrol and Thymol Attenuate Cytotoxicity Induced by Amyloid β(25-35 )via Activating Protein Kinase C and Inhibiting Oxidative Stress in PC12 Cells
por: Azizi, Zahra, et al.
Publicado: (2020)

Linagliptin Protects Human SH-SY5Y Neuroblastoma Cells against Amyloid-β Cytotoxicity via the Activation of Wnt1 and Suppression of IL-6 Release
por: Sedighi, Mohsen, et al.
Publicado: (2021)

Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy
por: Liu, Lili, et al.
Publicado: (2022)

Assessment of Probiotics Mixture on Memory Function, Inflammation Markers, and Oxidative Stress in an Alzheimer's Disease Model of Rats
por: Mehrabadi, Shima, et al.
Publicado: (2020)

Rational Design of Nitrogen-Doped Carbon Dots for Inhibiting β-Amyloid Aggregation
por: Liu, Hong, et al.
Publicado: (2023)

Inhibitory Potential of Acroptilon repens against Key Enzymes involved in Alzheimer and Diabetes, Phytochemical Profile, Radical Scavenging, and Antibacterial Activity
por: Afsharnezhad, Moslem, et al.
Publicado: (2021)

Dupilumab: An emerging therapy in allergic fungal rhinosinusitis()
por: Bulkhi, Adeeb A., et al.
Publicado: (2022)

Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition
por: Nedumpully-Govindan, Praveen, et al.
Publicado: (2016)

Imaging of fluorescent polymer dots in relation to channels and immune cells in the lymphatic system
por: Zhang, Yufan, et al.
Publicado: (2022)

Sulfuretin exerts diversified functions in the processing of amyloid precursor protein
por: Chen, Jian, et al.
Publicado: (2020)

Sex differences in a murine model of Cerebral Amyloid Angiopathy
por: Maniskas, Michael E., et al.
Publicado: (2021)

Cholesterol impacts the formation of huntingtin/lipid complexes and subsequent aggregation
por: Stonebraker, Alyssa R., et al.
Publicado: (2023)

X‐ray crystal structures of the type IVb secretion system DotB ATPases
por: Prevost, Marie S., et al.
Publicado: (2018)

Biomimetic semiconducting polymer dots for highly specific NIR-II fluorescence imaging of glioma
por: Men, Xiaoju, et al.
Publicado: (2022)

Tunable enzyme responses in amphiphilic nanoassemblies through alterations in the unimer–aggregate equilibrium
por: Gao, Jingjing, et al.
Publicado: (2019)

Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism
por: Gui, Xiao, et al.
Publicado: (2023)

J-aggregates albumin-based NIR-II fluorescent dye nanoparticles for cancer phototheranostics
por: Du, Bulin, et al.
Publicado: (2022)

Molecular insights into alginate β‐lactoglobulin A multivalencies—The foundation for their amorphous aggregates and coacervation
por: Madsen, Mikkel, et al.
Publicado: (2023)

Biomimetic macrophage membrane-coated gold-quantum dots with tumor microenvironment stimuli-responsive capability for tumor theranostic
por: Wang, Fan, et al.
Publicado: (2022)

Structural Remodeling Mechanism of the Toxic Amyloid Fibrillary Mediated by Epigallocatechin-3-gallate
por: Zhang, Nan, et al.
Publicado: (2022)

Characterization and engineering of the xylose-inducible xylP promoter for use in mold fungal species
por: Yap, Annie, et al.
Publicado: (2022)

Molecular insights into the primary nucleation of polymorphic amyloid β dimers in DOPC lipid bilayer membrane
por: Press‐Sandler, Olga, et al.
Publicado: (2022)

Amyloid-like nanofibrous network confined and aligned ultrafine bimetallic nanozymes for smart antibacterial therapy
por: Feng, Yonghai, et al.
Publicado: (2023)

Luminophore and Magnetic Multicore Nanoassemblies for Dual-Mode MRI and Fluorescence Imaging
por: Lartigue, Lénaïc, et al.
Publicado: (2019)

Modulation of β-amyloid aggregation by graphene quantum dots
por: Liu, Changliang, et al.
Publicado: (2019)

Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations
por: Buratti, Fiamma A., et al.
Publicado: (2022)

A peptide‐display protein scaffold to facilitate single molecule force studies of aggregation‐prone peptides
por: Doherty, Ciaran P. A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ufteh88qt5b3hujvsvj2179mg5