Melatonin Reduces Neuroinflammation and Improves Axonal Hypomyelination by Modulating M1/M2 Microglia Polarization via JAK2-STAT3-Telomerase Pathway in Postnatal Rats Exposed to Lipopolysaccharide

Microglia activation and associated inflammation are implicated in the periventricular white matter damage (PWMD) in septic postnatal rats. This study investigated whether melatonin would mitigate inflammation and alleviate the axonal hypomyelination in the corpus callosum in septic postnatal rats....

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Detalles Bibliográficos
Autores principales: Zhou, Qiuping, Lin, Lanfen, Li, Haiyan, Wang, Huifang, Jiang, Shuqi, Huang, Peixian, Lin, Qiongyu, Chen, Xuan, Deng, Yiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639545/
https://www.ncbi.nlm.nih.gov/pubmed/34585328
http://dx.doi.org/10.1007/s12035-021-02568-7

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