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Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging

PURPOSE: We aimed to use magnetic resonance imaging (MRI) to determine the relationship between the pathological depth of invasion (DOI), undetectability, and tumor thickness of squamous cell carcinoma of the floor of the mouth. MATERIALS AND METHODS: We retrospectively evaluated the relationship be...

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Autores principales: Baba, Akira, Hashimoto, Kazuhiko, Kuno, Hirofumi, Masuda, Koichi, Matsushima, Satoshi, Yamauchi, Hideomi, Ikeda, Koshi, Yamazaki, Masae, Taiki, Suzuki, Ogane, Satoru, Kurokawa, Ryo, Ota, Yoshiaki, Nomura, Takeshi, Ojiri, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639569/
https://www.ncbi.nlm.nih.gov/pubmed/34232443
http://dx.doi.org/10.1007/s11604-021-01161-1
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author Baba, Akira
Hashimoto, Kazuhiko
Kuno, Hirofumi
Masuda, Koichi
Matsushima, Satoshi
Yamauchi, Hideomi
Ikeda, Koshi
Yamazaki, Masae
Taiki, Suzuki
Ogane, Satoru
Kurokawa, Ryo
Ota, Yoshiaki
Nomura, Takeshi
Ojiri, Hiroya
author_facet Baba, Akira
Hashimoto, Kazuhiko
Kuno, Hirofumi
Masuda, Koichi
Matsushima, Satoshi
Yamauchi, Hideomi
Ikeda, Koshi
Yamazaki, Masae
Taiki, Suzuki
Ogane, Satoru
Kurokawa, Ryo
Ota, Yoshiaki
Nomura, Takeshi
Ojiri, Hiroya
author_sort Baba, Akira
collection PubMed
description PURPOSE: We aimed to use magnetic resonance imaging (MRI) to determine the relationship between the pathological depth of invasion (DOI), undetectability, and tumor thickness of squamous cell carcinoma of the floor of the mouth. MATERIALS AND METHODS: We retrospectively evaluated the relationship between pathological DOI and MRI detectability, as well as the relationship between pathological DOI and tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging or coronal T2-weighted imaging. RESULTS: We analyzed 30 patients with squamous cell carcinoma of the floor of the mouth; MRI revealed that the pathological DOI of the 11 undetectable lesions (median 2 mm) was smaller than that of the 19 detectable lesions (median 14 mm) (p < 0.001), and the cut-off value was 3 mm (sensitivity, 0.84; specificity, 0.91; area under the curve, 0.89). Tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging was assessed in all 19 detectable lesions; however, tumor thickness on coronal T2-weighted imaging could not be assessed in eight cases. Tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging was found to be significantly associated with the pathological DOI. CONCLUSIONS: Undetectability on MRI indicates superficial lesions with a pathological DOI value that is less than 3 mm. In detectable lesions, tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging is associated with pathological DOI.
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spelling pubmed-86395692021-12-03 Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging Baba, Akira Hashimoto, Kazuhiko Kuno, Hirofumi Masuda, Koichi Matsushima, Satoshi Yamauchi, Hideomi Ikeda, Koshi Yamazaki, Masae Taiki, Suzuki Ogane, Satoru Kurokawa, Ryo Ota, Yoshiaki Nomura, Takeshi Ojiri, Hiroya Jpn J Radiol Original Article PURPOSE: We aimed to use magnetic resonance imaging (MRI) to determine the relationship between the pathological depth of invasion (DOI), undetectability, and tumor thickness of squamous cell carcinoma of the floor of the mouth. MATERIALS AND METHODS: We retrospectively evaluated the relationship between pathological DOI and MRI detectability, as well as the relationship between pathological DOI and tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging or coronal T2-weighted imaging. RESULTS: We analyzed 30 patients with squamous cell carcinoma of the floor of the mouth; MRI revealed that the pathological DOI of the 11 undetectable lesions (median 2 mm) was smaller than that of the 19 detectable lesions (median 14 mm) (p < 0.001), and the cut-off value was 3 mm (sensitivity, 0.84; specificity, 0.91; area under the curve, 0.89). Tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging was assessed in all 19 detectable lesions; however, tumor thickness on coronal T2-weighted imaging could not be assessed in eight cases. Tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging was found to be significantly associated with the pathological DOI. CONCLUSIONS: Undetectability on MRI indicates superficial lesions with a pathological DOI value that is less than 3 mm. In detectable lesions, tumor thickness on coronal fat-suppressed contrast-enhanced T1-weighted imaging is associated with pathological DOI. Springer Singapore 2021-07-07 2021 /pmc/articles/PMC8639569/ /pubmed/34232443 http://dx.doi.org/10.1007/s11604-021-01161-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Baba, Akira
Hashimoto, Kazuhiko
Kuno, Hirofumi
Masuda, Koichi
Matsushima, Satoshi
Yamauchi, Hideomi
Ikeda, Koshi
Yamazaki, Masae
Taiki, Suzuki
Ogane, Satoru
Kurokawa, Ryo
Ota, Yoshiaki
Nomura, Takeshi
Ojiri, Hiroya
Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title_full Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title_fullStr Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title_full_unstemmed Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title_short Assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
title_sort assessment of squamous cell carcinoma of the floor of the mouth with magnetic resonance imaging
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639569/
https://www.ncbi.nlm.nih.gov/pubmed/34232443
http://dx.doi.org/10.1007/s11604-021-01161-1
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