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Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease

Clonal hematopoiesis of indeterminate potential (CHIP), defined by the presence of somatic mutations in hematopoietic cells, is associated with advanced age and increased mortality due to cardiovascular disease. Gene mutations in DNMT3A and TET2 are the most frequently identified variants among pati...

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Detalles Bibliográficos
Autores principales:	Cobo, Isidoro, Tanaka, Tiffany, Glass, Christopher K., Yeang, Calvin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	MYELOID BIOLOGY: Edited by Rafael Bejar
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639635/ https://www.ncbi.nlm.nih.gov/pubmed/34654019 http://dx.doi.org/10.1097/MOH.0000000000000688

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