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Periplocymarin Alleviates Doxorubicin-Induced Heart Failure and Excessive Accumulation of Ceramides

Doxorubicin-driven cardiotoxicity could result in dilated cardiomyopathy and heart failure (HF). Previously, we showed that periplocymarin exerted a cardiotonic role by promoting calcium influx and attenuating myocardial fibrosis induced by isoproterenol (ISO) by improving the metabolism of cardiomy...

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Detalles Bibliográficos
Autores principales: Yun, Weijing, Qian, Lei, Yuan, Ruqiang, Xu, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639694/
https://www.ncbi.nlm.nih.gov/pubmed/34869633
http://dx.doi.org/10.3389/fcvm.2021.732554

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