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Analysis at the single-cell level indicates an important role of heterogeneous global DNA methylation status on the progression of lung adenocarcinoma

Aberrant DNA modifications affect the tumorigenesis and progression of lung cancer. However, the global methylation status of tumor cells and the heterogeneous methylation status of cells within the same tumor need further study. We used publicly available single-cell RNAseq data to investigate the...

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Detalles Bibliográficos
Autores principales:	Chen, Quan-Fang, Gao, Han, Pan, Qing-Yun, Wang, Ying-Ju, Zhong, Xiao-Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639744/ https://www.ncbi.nlm.nih.gov/pubmed/34857857 http://dx.doi.org/10.1038/s41598-021-02786-y

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