Cargando…
Kindlin-2 deletion in osteoprogenitors causes severe chondrodysplasia and low-turnover osteopenia in mice
BACKGROUND: Our recent studies demonstrate that the focal adhesion protein Kindlin-2 exerts crucial functions in the mesenchymal stem cells, mature osteoblasts and osteocytes in control of early skeletal development and bone homeostasis in mice. However, whether Kindlin-2 plays a role in osteoprogen...
Autores principales: | Wu, Xiaohao, Qu, Minghao, Gong, Weiyuan, Zhou, Chunlei, Lai, Yumei, Xiao, Guozhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639803/ https://www.ncbi.nlm.nih.gov/pubmed/34934625 http://dx.doi.org/10.1016/j.jot.2021.08.005 |
Ejemplares similares
-
Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice
por: Lai, Yumei, et al.
Publicado: (2022) -
Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4(CreERT2) versus Aggrecan(CreERT2) transgene in mice
por: Yao, Qing, et al.
Publicado: (2023) -
Pip5k1c Loss in Chondrocytes Causes Spontaneous Osteoarthritic Lesions in Aged Mice
por: Qu, Minghao, et al.
Publicado: (2023) -
Kindlin-2 inhibits Nlrp3 inflammasome activation in nucleus pulposus to maintain homeostasis of the intervertebral disc
por: Chen, Sheng, et al.
Publicado: (2022) -
Loss of Pinch Proteins Causes Severe Degenerative Disc Disease-Like Lesions in Mice
por: Wu, Xiaohao, et al.
Publicado: (2023)