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Kindlin-2 deletion in osteoprogenitors causes severe chondrodysplasia and low-turnover osteopenia in mice

BACKGROUND: Our recent studies demonstrate that the focal adhesion protein Kindlin-2 exerts crucial functions in the mesenchymal stem cells, mature osteoblasts and osteocytes in control of early skeletal development and bone homeostasis in mice. However, whether Kindlin-2 plays a role in osteoprogen...

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Detalles Bibliográficos
Autores principales: Wu, Xiaohao, Qu, Minghao, Gong, Weiyuan, Zhou, Chunlei, Lai, Yumei, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639803/
https://www.ncbi.nlm.nih.gov/pubmed/34934625
http://dx.doi.org/10.1016/j.jot.2021.08.005

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