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Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis

Osteoarthritis (OA) is significantly associated with diabetes, but how hyperglycemia induces or aggravates OA has not been shown. The synovium plays a critical role in cartilage metabolism and substance exchange. Herein, we intended to investigate whether and how hyperglycemia affects the occurrence...

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Detalles Bibliográficos
Autores principales: Li, Qingxian, Wen, Yinxian, Wang, Linlong, Chen, Biao, Chen, Jun, Wang, Hui, Chen, Liaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639977/
https://www.ncbi.nlm.nih.gov/pubmed/34759325
http://dx.doi.org/10.1038/s12276-021-00697-6