Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver

Non-human primates (NHPs) represent the most valuable animals for drug discovery. However, the current main challenge remains that the NHP has not yet been used to develop an efficient translational medicine platform simulating human diseases, such as cancer. This study generated an in situ gene-edi...

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Detalles Bibliográficos
Autores principales: Zhong, Liping, Huang, Yong, He, Jian, Yang, Nuo, Xu, Banghao, Ma, Yun, Liu, Junjie, Tang, Chao, Luo, Chengpiao, Wu, Pan, Lai, Zongqiang, Huo, Yu, Lu, Tao, Huang, Dongni, Gong, Wenlin, Gan, Lu, Luo, Yiqun, Zhang, Zhikun, Liu, Xiyu, Zhao, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640017/
https://www.ncbi.nlm.nih.gov/pubmed/34857736
http://dx.doi.org/10.1038/s41392-021-00799-7

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