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The optics of the human eye at 8.6 µm resolution

Ocular optics is normally estimated based on up to 2,600 measurement points within the pupil of the eye, which implies a lateral resolution of approximately 175 µm for a 9 mm pupil diameter. This is because information below this resolution is not thought to be relevant or even possible to obtain wi...

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Autores principales: Bonaque-González, Sergio, Trujillo-Sevilla, Juan M., Velasco-Ocaña, Miriam, Casanova-González, Óscar, Sicilia-Cabrera, Miguel, Roqué-Velasco, Alex, Ceruso, Sabato, Oliva-García, Ricardo, Martín-Hernández, Javier, Gomez-Cardenes, Oscar, Marichal-Hernández, José G., Gatinel, Damien, Holladay, Jack T., Rodríguez-Ramos, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640020/
https://www.ncbi.nlm.nih.gov/pubmed/34857820
http://dx.doi.org/10.1038/s41598-021-02653-w
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author Bonaque-González, Sergio
Trujillo-Sevilla, Juan M.
Velasco-Ocaña, Miriam
Casanova-González, Óscar
Sicilia-Cabrera, Miguel
Roqué-Velasco, Alex
Ceruso, Sabato
Oliva-García, Ricardo
Martín-Hernández, Javier
Gomez-Cardenes, Oscar
Marichal-Hernández, José G.
Gatinel, Damien
Holladay, Jack T.
Rodríguez-Ramos, José M.
author_facet Bonaque-González, Sergio
Trujillo-Sevilla, Juan M.
Velasco-Ocaña, Miriam
Casanova-González, Óscar
Sicilia-Cabrera, Miguel
Roqué-Velasco, Alex
Ceruso, Sabato
Oliva-García, Ricardo
Martín-Hernández, Javier
Gomez-Cardenes, Oscar
Marichal-Hernández, José G.
Gatinel, Damien
Holladay, Jack T.
Rodríguez-Ramos, José M.
author_sort Bonaque-González, Sergio
collection PubMed
description Ocular optics is normally estimated based on up to 2,600 measurement points within the pupil of the eye, which implies a lateral resolution of approximately 175 µm for a 9 mm pupil diameter. This is because information below this resolution is not thought to be relevant or even possible to obtain with current measurement systems. In this work, we characterize the in vivo ocular optics of the human eye with a lateral resolution of 8.6 µm, which implies roughly 1 million measurement points for a pupil diameter of 9 mm. The results suggest that the normal human eye presents a series of hitherto unknown optical patterns with amplitudes between 200 and 300 nm and is made up of a series of in-phase peaks and valleys. If the results are analysed at only high lateral frequencies, the human eye is also found to contain a whole range of new information. This discovery could have a great impact on the way we understand some fundamental mechanisms of human vision and could be of outstanding utility in certain fields of ophthalmology.
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spelling pubmed-86400202021-12-06 The optics of the human eye at 8.6 µm resolution Bonaque-González, Sergio Trujillo-Sevilla, Juan M. Velasco-Ocaña, Miriam Casanova-González, Óscar Sicilia-Cabrera, Miguel Roqué-Velasco, Alex Ceruso, Sabato Oliva-García, Ricardo Martín-Hernández, Javier Gomez-Cardenes, Oscar Marichal-Hernández, José G. Gatinel, Damien Holladay, Jack T. Rodríguez-Ramos, José M. Sci Rep Article Ocular optics is normally estimated based on up to 2,600 measurement points within the pupil of the eye, which implies a lateral resolution of approximately 175 µm for a 9 mm pupil diameter. This is because information below this resolution is not thought to be relevant or even possible to obtain with current measurement systems. In this work, we characterize the in vivo ocular optics of the human eye with a lateral resolution of 8.6 µm, which implies roughly 1 million measurement points for a pupil diameter of 9 mm. The results suggest that the normal human eye presents a series of hitherto unknown optical patterns with amplitudes between 200 and 300 nm and is made up of a series of in-phase peaks and valleys. If the results are analysed at only high lateral frequencies, the human eye is also found to contain a whole range of new information. This discovery could have a great impact on the way we understand some fundamental mechanisms of human vision and could be of outstanding utility in certain fields of ophthalmology. Nature Publishing Group UK 2021-12-02 /pmc/articles/PMC8640020/ /pubmed/34857820 http://dx.doi.org/10.1038/s41598-021-02653-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Bonaque-González, Sergio
Trujillo-Sevilla, Juan M.
Velasco-Ocaña, Miriam
Casanova-González, Óscar
Sicilia-Cabrera, Miguel
Roqué-Velasco, Alex
Ceruso, Sabato
Oliva-García, Ricardo
Martín-Hernández, Javier
Gomez-Cardenes, Oscar
Marichal-Hernández, José G.
Gatinel, Damien
Holladay, Jack T.
Rodríguez-Ramos, José M.
The optics of the human eye at 8.6 µm resolution
title The optics of the human eye at 8.6 µm resolution
title_full The optics of the human eye at 8.6 µm resolution
title_fullStr The optics of the human eye at 8.6 µm resolution
title_full_unstemmed The optics of the human eye at 8.6 µm resolution
title_short The optics of the human eye at 8.6 µm resolution
title_sort optics of the human eye at 8.6 µm resolution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640020/
https://www.ncbi.nlm.nih.gov/pubmed/34857820
http://dx.doi.org/10.1038/s41598-021-02653-w
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