Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2

SARS-CoV-2-specific CD8(+) T cells are scarce but detectable in unexposed healthy donors (UHDs). It remains unclear whether pre-existing human coronavirus (HCoV)-specific CD8(+) T cells are converted to functionally competent T cells cross-reactive to SARS-CoV-2. Here, we identified the HLA-A24-high...

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Detalles Bibliográficos
Autores principales: Shimizu, Kanako, Iyoda, Tomonori, Sanpei, An, Nakazato, Hiroshi, Okada, Masahiro, Ueda, Shogo, Kato-Murayama, Miyuki, Murayama, Kazutaka, Shirouzu, Mikako, Harada, Naoko, Hidaka, Michihiro, Fujii, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640030/
https://www.ncbi.nlm.nih.gov/pubmed/34857854
http://dx.doi.org/10.1038/s42003-021-02885-6

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