Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Yolk sac (YS) hematopoiesis is critical for the survival of the embryo and a major source of tissue-resident macrophages that persist into adulthood. Yet, the transcriptional and epigenetic regulation of YS hematopoiesis remains poorly characterized. Here we report that the epigenetic regulator Ezh2...

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Detalles Bibliográficos
Autores principales: Neo, Wen Hao, Meng, Yiran, Rodriguez-Meira, Alba, Fadlullah, Muhammad Z. H., Booth, Christopher A. G., Azzoni, Emanuele, Thongjuea, Supat, de Bruijn, Marella F. T. R., Jacobsen, Sten Eirik W., Mead, Adam J., Lacaud, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640066/
https://www.ncbi.nlm.nih.gov/pubmed/34857757
http://dx.doi.org/10.1038/s41467-021-27140-8

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