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Cancer-Associated Fibroblasts Promote the Upregulation of PD-L1 Expression Through Akt Phosphorylation in Colorectal Cancer

Upregulation of immune checkpoint proteins is one of the main mechanisms for tumor immune escape. The expression of programmed death ligand-1 (PD-L1) in colorectal cancer (CRC) is higher than in normal colorectal epithelial tissue, and patients with higher PD-L1 expression have a poorer prognosis. A...

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Detalles Bibliográficos
Autores principales:	Gao, Yang, Sun, Zhao, Gu, Junjie, Li, Zhe, Xu, Xiuxiu, Xue, Chunling, Li, Xuechun, Zhao, Lin, Zhou, Jianfeng, Bai, Chunmei, Han, Qin, Zhao, Robert Chunhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640083/ https://www.ncbi.nlm.nih.gov/pubmed/34868949 http://dx.doi.org/10.3389/fonc.2021.748465

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