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Melanocortin 1 Receptor Deficiency in Hematopoietic Cells Promotes the Expansion of Inflammatory Leukocytes in Atherosclerotic Mice

Melanocortin receptor 1 (MC1-R) is expressed in leukocytes, where it mediates anti-inflammatory actions. We have previously observed that global deficiency of MC1-R signaling perturbs cholesterol homeostasis, increases arterial leukocyte accumulation and accelerates atherosclerosis in apolipoprotein...

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Detalles Bibliográficos
Autores principales:	Kadiri, James J., Tadayon, Sina, Thapa, Keshav, Suominen, Anni, Hollmén, Maija, Rinne, Petteri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640177/ https://www.ncbi.nlm.nih.gov/pubmed/34868038 http://dx.doi.org/10.3389/fimmu.2021.774013

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