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Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival

Random flaps are widely used in tissue reconstruction, attributed to the lack of vascular axial limitation. Nevertheless, the distal end of the flap is prone to necrosis due to the lack of blood supply. Notoginseng triterpenes (NTs) are the active components extracted from Panax notoginseng, reducin...

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Detalles Bibliográficos
Autores principales: Huang, Zhiyang, Luo, Xiaobin, Zhang, Yifan, Ying, Yibo, Cai, Xiong, Lu, Wenjie, Zhao, Juan, Wang, Yutian, Lin, Wenwei, Tu, Yurong, Xiang, Ziyue, Wu, Qiuji, Yang, Shengwu, Zhu, Sipin, Li, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640242/
https://www.ncbi.nlm.nih.gov/pubmed/34869285
http://dx.doi.org/10.3389/fbioe.2021.771066