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Surrogate endpoints for early-stage breast cancer: a review of the state of the art, controversies, and future prospects
Drug approval for early-stage breast cancer (EBC) has been historically granted in the context of registration trials based on adequate outcomes such as disease-free survival and overall survival. Improvements in long-term outcomes have made it more difficult to demonstrate the clinical benefit of a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640314/ https://www.ncbi.nlm.nih.gov/pubmed/34868353 http://dx.doi.org/10.1177/17588359211059587 |