Methylation and Expression of Mutant FUS in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disease leading to degeneration of motor neurons (MNs). Epigenetic modification of gene expression is increasingly recognized as potential disease mechanism. In the present study we generated motor neurons from induced pluripotent stem cel...

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Detalles Bibliográficos
Autores principales: Hartung, T., Rhein, M., Kalmbach, N., Thau-Habermann, N., Naujock, M., Müschen, L., Frieling, H., Sterneckert, J., Hermann, A., Wegner, F., Petri, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640347/
https://www.ncbi.nlm.nih.gov/pubmed/34869374
http://dx.doi.org/10.3389/fcell.2021.774751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640347/
https://www.ncbi.nlm.nih.gov/pubmed/34869374
http://dx.doi.org/10.3389/fcell.2021.774751

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