Cargando…

Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos

Purpose: This study aimed to establish a non-invasive predicting model via Raman spectroscopy for evaluating the blastocyst development potential of day 3 high-quality cleavage stage embryos. Methods: Raman spectroscopy was used to detect the metabolic spectrum of spent day 3 (D3) embryo culture med...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Wei, Zhang, Shuoping, Gu, Yifan, Gong, Fei, Kong, Lingyin, Lu, Guangxiu, Lin, Ge, Liang, Bo, Hu, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640355/ https://www.ncbi.nlm.nih.gov/pubmed/34867485 http://dx.doi.org/10.3389/fphys.2021.777259

Ejemplares similares

Raman spectroscopy on live mouse early embryo while it continues to develop into blastocyst in vitro
por: Perevedentseva, Elena, et al.
Publicado: (2019)

The Association Between Embryo Quality, Number of Transferred Embryos and Live Birth Rate After Vitrified Cleavage-Stage Embryos and Blastocyst Transfer
por: Zhu, Qianqian, et al.
Publicado: (2020)

Glycans in spent embryo culture medium are related to the implantation ability of blastocysts
por: Wang, Dongyang, et al.
Publicado: (2023)

Non-invasive Amino Acid Profiling of Embryo Culture Medium Using HPLC Correlates With Embryo Implantation Potential in Women Undergoing in vitro Fertilization
por: Huo, Peng, et al.
Publicado: (2020)

The Relationship between Cell Number, Division Behavior and Developmental Potential of Cleavage Stage Human Embryos: A Time-Lapse Study
por: Kong, Xiangyi, et al.
Publicado: (2016)

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts
por: D’Souza, Fiona, et al.
Publicado: (2018)

Vacuolization in embryos on days 3 and 4 of in vitro development: Association with stimulation protocols, embryo development, chromosomal status, pregnancy and neonatal outcomes
por: Chen, Longbin, et al.
Publicado: (2022)

The Valuable Reference of Live Birth Rate in the Single Vitrified-Warmed BB/BC/CB Blastocyst Transfer: The Cleavage-Stage Embryo Quality and Embryo Development Speed
por: Shen, Xi, et al.
Publicado: (2020)

Associations of post-warming embryo or blastocyst development with clinical pregnancy in vitrified embryo or blastocyst transfer cycles
por: Hong, Yeon Hee, et al.
Publicado: (2020)

Impact of Day 7 Blastocyst Transfer on Obstetric and Perinatal Outcome of Singletons Born After Vitrified-Warmed Embryo Transfer
por: Huang, Jiaan, et al.
Publicado: (2020)

An increase of phosphatidylcholines in follicular fluid implies attenuation of embryo quality on day 3 post-fertilization
por: Wang, Ju, et al.
Publicado: (2021)

Embryo development until blastocyst stage with and without renewal of single medium on day 3
por: Peña, Fernando, et al.
Publicado: (2018)

Clinical and neonatal outcomes of patients of different ages following transfer of thawed cleavage embryos and blastocysts cultured from thawed cleavage-stage embryos
por: Zhou, Qin-Wei, et al.
Publicado: (2018)

Publisher Correction to: An increase of phosphatidylcholines in follicular fluid implies attenuation of embryo quality on day 3 post-fertilization
por: Wang, Ju, et al.
Publicado: (2021)

Non-invasive preimplantation genetic testing for conventional IVF blastocysts
por: Xie, Pingyuan, et al.
Publicado: (2022)

Identification of Novel Variants of Thyroid Hormone Receptor Interaction Protein 13 That Cause Female Infertility Characterized by Zygotic Cleavage Failure
por: Hu, Huiling, et al.
Publicado: (2022)

An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
por: Liu, Longqi, et al.
Publicado: (2019)

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
por: Høgset, Håkon, et al.
Publicado: (2020)

Building Principles for Constructing a Mammalian Blastocyst Embryo
por: Pfeffer, Peter L.
Publicado: (2018)

Monozygotic twinning following embryo biopsy at the blastocyst stage
por: Sellers, Rafael, et al.
Publicado: (2021)

Is Blastocyst Culture Responsible for Higher Pregnancy Rates? A Critical Analysis of the Day of Optimal Embryo Transfer and Embryo Quality
por: Günther, Veronika, et al.
Publicado: (2022)

Prediction model for day 3 embryo implantation potential based on metabolites in spent embryo culture medium
por: Liang, Rong, et al.
Publicado: (2023)

Evaluation of Laser Confocal Raman Spectroscopy as a Non-Invasive Method for Detecting Sperm DNA Contents
por: Li, Mengge, et al.
Publicado: (2022)

Naive stem cell blastocyst model captures human embryo lineage segregation
por: Yanagida, Ayaka, et al.
Publicado: (2021)

Blastocyst-stage embryos provide better frozen-thawed embryo transfer outcomes for young patients with previous fresh embryo transfer failure
por: Fang, Lanlan, et al.
Publicado: (2020)

Simulating the Mammalian Blastocyst - Molecular and Mechanical Interactions Pattern the Embryo
por: Krupinski, Pawel, et al.
Publicado: (2011)

Blastocyst stage transfer vs cleavage stage embryo transfer
por: Mangalraj, Ann M, et al.
Publicado: (2009)

Telomere lengths in human oocytes, cleavage stage embryos and blastocysts
por: Turner, S., et al.
Publicado: (2010)

Blastocyst Morphology Holds Clues Concerning The Chromosomal Status of The Embryo
por: Savio Figueira, Rita de Cassia, et al.
Publicado: (2015)

Reproductive outcomes of retransferring retained embryos in blastocyst transfer cycles
por: Yi, Hyun Jeong, et al.
Publicado: (2016)

The Landscape of Telomere Length and Telomerase in Human Embryos at Blastocyst Stage
por: Wang, Fang, et al.
Publicado: (2023)

Impaired Blastocyst Formation in Lnx2-Knockdown Mouse Embryos
por: Lee, Seung-Jae, et al.
Publicado: (2023)

The Quiet Embryo Hypothesis: 20 years on
por: Leese, Henry J., et al.
Publicado: (2022)

Granulocyte-Macrophage Colony Stimulating Factor in Single Blastocyst Conditioned Medium as a Biomarker for Predicting Implantation Outcome of Embryo
por: Chen, Peilin, et al.
Publicado: (2021)

Poor Embryo Quality Is Associated With A Higher Risk of Low Birthweight in Vitrified-Warmed Single Embryo Transfer Cycles
por: Huang, Jiaan, et al.
Publicado: (2020)

Comparison of elective single cleavage-embryo transfer to elective single blastocyst-embryo transfer in human IVF-ET
por: Kang, Sang Min, et al.
Publicado: (2011)

Fused blastocysts as a consequence of group embryo culture: observations, complications, and potential solutions
por: Swain, Jason E.
Publicado: (2020)

Reciprocal Translocation Carrier Diagnosis in Preimplantation Human Embryos
por: Hu, Liang, et al.
Publicado: (2016)

Influence of hypomagnetic field on the heartbeat in zebrafish embryos
por: Krylov, Viacheslav, et al.
Publicado: (2022)

Self-diploidization of human haploid parthenogenetic embryos through the Rho pathway regulates endomitosis and failed cytokinesis
por: Leng, Lizhi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9gbbg8rk1veajoko4cupfiebop