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Donor acquired visceral leishmaniasis following liver transplantation
Patients who undergo solid organ transplantation are at risk of opportunistic infection associated with immunosuppression. We report a case of confirmed donor derived visceral leishmaniasis (VL), in a patient following liver transplantation causing fever and pancytopenia. The diagnosis was confirmed...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640386/ https://www.ncbi.nlm.nih.gov/pubmed/34917328 http://dx.doi.org/10.1136/flgastro-2020-101659 |
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author | Dhaliwal, Amritpal Chauhan, Abhishek Aggarwal, Dinesh Davda, Pretin David, Miruna Amel-Kashipaz, Rasoul Brown, Rachel Dedicoat, Martin Clark, Fiona Shah, Tahir Elsharkawy, Ahmed Mohamed Ushiro-Lumb, Ines Chiodini, Peter El-Sherif, Omar Armstrong, Matthew Ferguson, James W |
author_facet | Dhaliwal, Amritpal Chauhan, Abhishek Aggarwal, Dinesh Davda, Pretin David, Miruna Amel-Kashipaz, Rasoul Brown, Rachel Dedicoat, Martin Clark, Fiona Shah, Tahir Elsharkawy, Ahmed Mohamed Ushiro-Lumb, Ines Chiodini, Peter El-Sherif, Omar Armstrong, Matthew Ferguson, James W |
author_sort | Dhaliwal, Amritpal |
collection | PubMed |
description | Patients who undergo solid organ transplantation are at risk of opportunistic infection associated with immunosuppression. We report a case of confirmed donor derived visceral leishmaniasis (VL), in a patient following liver transplantation causing fever and pancytopenia. The diagnosis was confirmed by bone marrow biopsy, with confirmed positive donor serology, with no other route of transmission. To our knowledge, this is the first case report in the United Kingdom and Europe, of confirmed organ donor transmission of VL. This case report highlights an important consideration of donor derived infections, in the context of solid organ transplantation. |
format | Online Article Text |
id | pubmed-8640386 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-86403862021-12-15 Donor acquired visceral leishmaniasis following liver transplantation Dhaliwal, Amritpal Chauhan, Abhishek Aggarwal, Dinesh Davda, Pretin David, Miruna Amel-Kashipaz, Rasoul Brown, Rachel Dedicoat, Martin Clark, Fiona Shah, Tahir Elsharkawy, Ahmed Mohamed Ushiro-Lumb, Ines Chiodini, Peter El-Sherif, Omar Armstrong, Matthew Ferguson, James W Frontline Gastroenterol Liver Patients who undergo solid organ transplantation are at risk of opportunistic infection associated with immunosuppression. We report a case of confirmed donor derived visceral leishmaniasis (VL), in a patient following liver transplantation causing fever and pancytopenia. The diagnosis was confirmed by bone marrow biopsy, with confirmed positive donor serology, with no other route of transmission. To our knowledge, this is the first case report in the United Kingdom and Europe, of confirmed organ donor transmission of VL. This case report highlights an important consideration of donor derived infections, in the context of solid organ transplantation. BMJ Publishing Group 2021-01-04 /pmc/articles/PMC8640386/ /pubmed/34917328 http://dx.doi.org/10.1136/flgastro-2020-101659 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Liver Dhaliwal, Amritpal Chauhan, Abhishek Aggarwal, Dinesh Davda, Pretin David, Miruna Amel-Kashipaz, Rasoul Brown, Rachel Dedicoat, Martin Clark, Fiona Shah, Tahir Elsharkawy, Ahmed Mohamed Ushiro-Lumb, Ines Chiodini, Peter El-Sherif, Omar Armstrong, Matthew Ferguson, James W Donor acquired visceral leishmaniasis following liver transplantation |
title | Donor acquired visceral leishmaniasis following liver transplantation |
title_full | Donor acquired visceral leishmaniasis following liver transplantation |
title_fullStr | Donor acquired visceral leishmaniasis following liver transplantation |
title_full_unstemmed | Donor acquired visceral leishmaniasis following liver transplantation |
title_short | Donor acquired visceral leishmaniasis following liver transplantation |
title_sort | donor acquired visceral leishmaniasis following liver transplantation |
topic | Liver |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640386/ https://www.ncbi.nlm.nih.gov/pubmed/34917328 http://dx.doi.org/10.1136/flgastro-2020-101659 |
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