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Vitamin C Rescues in vitro Embryonic Development by Correcting Impaired Active DNA Demethylation

During preimplantation development, a wave of genome-wide DNA demethylation occurs to acquire a hypomethylated genome of the blastocyst. As an essential epigenomic event, postfertilization DNA demethylation is critical to establish full developmental potential. Despite its importance, this process i...

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Detalles Bibliográficos
Autores principales:	Chu, Meiqiang, Yao, Fusheng, Xi, Guangyin, Yang, Jiajun, Zhang, Zhenni, Yang, Qianying, Tian, Jianhui, An, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640463/ https://www.ncbi.nlm.nih.gov/pubmed/34869387 http://dx.doi.org/10.3389/fcell.2021.784244

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