Indoleamine 2, 3-Dioxygenase Promotes Aryl Hydrocarbon Receptor-Dependent Differentiation Of Regulatory B Cells in Lung Cancer

Regulatory B cells (Breg) are IL-10 producing subsets of B cells that contribute to immunosuppression in the tumor microenvironment (TME). Breg are elevated in patients with lung cancer; however, the mechanisms underlying Breg development and their function in lung cancer have not been adequately el...

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Detalles Bibliográficos
Autores principales: Tousif, Sultan, Wang, Yong, Jackson, Joshua, Hough, Kenneth P., Strenkowski, John G., Athar, Mohammad, Thannickal, Victor J., McCusker, Robert H., Ponnazhagan, Selvarangan, Deshane, Jessy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640488/
https://www.ncbi.nlm.nih.gov/pubmed/34867973
http://dx.doi.org/10.3389/fimmu.2021.747780

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