Roles of Nitric Oxide in the Regulation of Reproduction: A Review

Nitric oxide (NO) has attracted significant attention as a stellar molecule. Presently, the study of NO has penetrated every field of life science, and NO is widely distributed in various tissues and organs. This review demonstrates the importance of NO in both male and female reproductive processes...

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Autores principales: Luo, Yuxin, Zhu, Yanbin, Basang, Wangdui, Wang, Xin, Li, Chunjin, Zhou, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640491/
https://www.ncbi.nlm.nih.gov/pubmed/34867795
http://dx.doi.org/10.3389/fendo.2021.752410
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author Luo, Yuxin
Zhu, Yanbin
Basang, Wangdui
Wang, Xin
Li, Chunjin
Zhou, Xu
author_facet Luo, Yuxin
Zhu, Yanbin
Basang, Wangdui
Wang, Xin
Li, Chunjin
Zhou, Xu
author_sort Luo, Yuxin
collection PubMed
description Nitric oxide (NO) has attracted significant attention as a stellar molecule. Presently, the study of NO has penetrated every field of life science, and NO is widely distributed in various tissues and organs. This review demonstrates the importance of NO in both male and female reproductive processes in numerous ways, such as in neuromodulation, follicular and oocyte maturation, ovulation, corpus luteum degeneration, fertilization, implantation, pregnancy maintenance, labor and menstrual cycle regulation, spermatogenesis, sperm maturation, and reproduction. However, the mechanism of action of some NO is still unknown, and understanding its mechanism may contribute to the clinical treatment of some reproductive diseases.
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spelling pubmed-86404912021-12-04 Roles of Nitric Oxide in the Regulation of Reproduction: A Review Luo, Yuxin Zhu, Yanbin Basang, Wangdui Wang, Xin Li, Chunjin Zhou, Xu Front Endocrinol (Lausanne) Endocrinology Nitric oxide (NO) has attracted significant attention as a stellar molecule. Presently, the study of NO has penetrated every field of life science, and NO is widely distributed in various tissues and organs. This review demonstrates the importance of NO in both male and female reproductive processes in numerous ways, such as in neuromodulation, follicular and oocyte maturation, ovulation, corpus luteum degeneration, fertilization, implantation, pregnancy maintenance, labor and menstrual cycle regulation, spermatogenesis, sperm maturation, and reproduction. However, the mechanism of action of some NO is still unknown, and understanding its mechanism may contribute to the clinical treatment of some reproductive diseases. Frontiers Media S.A. 2021-11-19 /pmc/articles/PMC8640491/ /pubmed/34867795 http://dx.doi.org/10.3389/fendo.2021.752410 Text en Copyright © 2021 Luo, Zhu, Basang, Wang, Li and Zhou https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Luo, Yuxin
Zhu, Yanbin
Basang, Wangdui
Wang, Xin
Li, Chunjin
Zhou, Xu
Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title_full Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title_fullStr Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title_full_unstemmed Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title_short Roles of Nitric Oxide in the Regulation of Reproduction: A Review
title_sort roles of nitric oxide in the regulation of reproduction: a review
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640491/
https://www.ncbi.nlm.nih.gov/pubmed/34867795
http://dx.doi.org/10.3389/fendo.2021.752410
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