Cargando…

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1

Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia, tumour cells secrete pro‐angiogenic factors to induce blood vessel formation and restore oxygen supply to hypoxic regions. Extracellular vesicle...

Descripción completa

Detalles Bibliográficos
Autores principales: Keulers, Tom G., Libregts, Sten F., Beaumont, Joel E.J., Savelkouls, Kim G., Bussink, Johan, Duimel, Hans, Dubois, Ludwig, Zonneveld, Marijke I., López‐Iglesias, Carmen, Bezstarosti, Karel, Demmers, Jeroen A., Vooijs, Marc, Wauben, Marca, Rouschop, Kasper M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640512/
https://www.ncbi.nlm.nih.gov/pubmed/34859607
http://dx.doi.org/10.1002/jev2.12166