Cargando…

Protocol for a prospective double-blind, randomised, placebo-controlled feasibility trial of octreotide infusion during liver transplantation

INTRODUCTION: Liver transplantation is a complex operation that can provide significant improvements in quality of life and survival to the recipients. However, serious complications are common and include major haemorrhage, hypotension and renal failure. Blood transfusion and the development of acu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fabes, Jeremy, Ambler, Gareth, Shah, Bina, Williams, Norman R, Martin, Daniel, Davidson, Brian R, Spiro, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Anaesthesia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640665/ https://www.ncbi.nlm.nih.gov/pubmed/34857585 http://dx.doi.org/10.1136/bmjopen-2021-055864

Ejemplares similares

Effect of a continuous perineural levobupivacaine infusion on pain after major lower limb amputation: a randomised double-blind placebo-controlled trial
por: Hunt, William, et al.
Publicado: (2023)

Study protocol for a double blind, randomised, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy: SUB-pectoral Local anaesthetic Infusion following MastEctomy (SUBLIME) study
por: Langford, R, et al.
Publicado: (2014)

Subcutaneous sumatriptan for the treatment of postcraniotomy pain (SUPS trial): protocol for a randomised double-blinded placebo controlled trial
por: Licina, Ana, et al.
Publicado: (2019)

Angiotensin II in liver transplantation (AngLT-1): protocol of a randomised, double-blind, placebo-controlled trial
por: Bokoch, Michael P, et al.
Publicado: (2023)

Impact of dexmedetomidine infusion during general anaesthesia on incidence of postoperative delirium in elderly patients after major non-cardiac surgery: study protocol of a randomised, double-blinded and placebo-controlled trial
por: Wang, Bo-Jie, et al.
Publicado: (2018)

Protocol for a randomised, double-blind, placebo-controlled trial to explore the effect of tramadol in the prevention of postpartum depression (ETPPD)
por: Duan, Guangyou, et al.
Publicado: (2018)

Argipressin for prevention of blood loss during liver resection: a study protocol for a randomised, placebo-controlled, double-blinded trial (ARG-01)
por: Wisén, Ellinor, et al.
Publicado: (2023)

Erector spinae plane block for minimally invasive mitral valve surgery: a double-blind, prospective, randomised placebo-controlled trial—a study protocol
por: Hoogma, Danny Feike, et al.
Publicado: (2021)

Assessing the effectiveness of perioperative s-ketamine on new-onset headache after resective epilepsy surgery (ESPAIN-trial): protocol for a randomised, double-blind, placebo-controlled trial
por: Sloekers, Jiske Cornelia Theresa, et al.
Publicado: (2019)

Protocol of DEXPED trial: efficacy of intravenous dexamethasone, administered at the time of analgesic blocking of the lower limb, on postoperative pain in children: a randomised, placebo-controlled, double-blind trial
por: Vautrin, Nicolas, et al.
Publicado: (2020)

Dexmedetomidine after deep brain stimulation for prevention of delirium in elderly patients with Parkinson’s disease: protocol for a single-centre, randomised, double-blind, placebo-controlled trial in China
por: Yao, Jingxin, et al.
Publicado: (2023)

Study protocol for a pilot, randomised, double-blinded, placebo controlled trial of perineural local anaesthetics and steroids for chronic post-traumatic neuropathic pain in the ankle and foot: the PREPLANS study
por: Bhatia, Anuj, et al.
Publicado: (2016)

Fluoxetine for reducing postoperative cognitive dysfunction in elderly patients after total knee replacement: study protocol for a single-centre, double-blind, randomised, parallel-group, superiority, placebo-controlled trial
por: Lin, Daoyi, et al.
Publicado: (2022)

Efficacy of systemic lidocaine in postoperative delirium in elderly patients undergoing laparoscopic colorectal surgery: study protocol for a multicentre, prospective, double-blind, randomised, parallel-group, superiority, placebo-controlled trial
por: Liao, Xincheng, et al.
Publicado: (2022)

Effectiveness, cost-effectiveness and safety of gabapentin versus placebo as an adjunct to multimodal pain regimens in surgical patients: protocol of a placebo controlled randomised controlled trial with blinding (GAP study)
por: Baos, Sarah, et al.
Publicado: (2020)

Randomised, double-blind controlled trial by dose reduction of implanted intrathecal morphine delivery in chronic non-cancer pain
por: Raphael, Jon H, et al.
Publicado: (2013)

Safety and efficacy of tranexamic acid in paediatric cardiac surgery: study protocol for a double-blind randomised controlled trial
por: Zhang, Yu, et al.
Publicado: (2019)

Effects of subanaesthetic S-ketamine on postoperative delirium and cognitive function in elderly patients undergoing non-cardiac thoracic surgery: a protocol for a randomised, double-blinded, placebo-controlled and positive-controlled, non-inferiority trial (SKED trial)
por: Wei, Wei, et al.
Publicado: (2022)

Effect of perioperative levosimendan administration on postoperative N-terminal pro-B-type natriuretic peptide concentration in patients with increased cardiovascular risk factors undergoing non-cardiac surgery: protocol for the double-blind, randomised, placebo-controlled IMPROVE trial
por: Reiterer, Christian, et al.
Publicado: (2022)

Tight perioperative blood pressure management to reduce complications: a randomised feasibility trial
por: Li, Kai, et al.
Publicado: (2023)

Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial
por: Steiness, Joakim, et al.
Publicado: (2022)

Effect of intratracheal dexmedetomidine administration on recovery from general anaesthesia after gynaecological laparoscopic surgery: a randomised double-blinded study
por: Wang, Fei, et al.
Publicado: (2018)

Phase II double-blind randomised controlled trial of exogenous administration of melatonin in chronic pain (DREAM—CP): a study protocol
por: Adam, Rosalind, et al.
Publicado: (2020)

Understanding recruitment to a perioperative randomised controlled trial: protocol for a mixed-methods substudy nested within a feasibility trial of octreotide infusion during liver transplantation
por: Brodkin, Edgar, et al.
Publicado: (2022)

Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial)
por: Mazer, C David, et al.
Publicado: (2023)

PACMAN trial protocol, Perioperative Administration of Corticotherapy on Morbidity and mortality After Non-cardiac major surgery: a randomised, multicentre, double-blind, superiority study
por: Asehnoune, Karim, et al.
Publicado: (2019)

Ultrasound-guided bilateral pudendal nerve blocks of nulliparous women with epidural labour analgesia in the second stage of labour: a randomised, double-blind, controlled trial
por: Xu, Jialing, et al.
Publicado: (2020)

Efficacy of the Gelstix nucleus augmentation device for the treatment of chronic discogenic low back pain: protocol for a randomised, sham-controlled, double-blind, multicentre trial
por: Koetsier, Eva, et al.
Publicado: (2022)

Effects of pericapsular nerve group (PENG) block on postoperative recovery in elderly patients with hip fracture: study protocol for a randomised, parallel controlled, double-blind trial
por: Luo, Wei, et al.
Publicado: (2022)

Intraoperative infusion of dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing craniotomy: a protocol of randomised clinical trial
por: Cui, Qianyu, et al.
Publicado: (2023)

Comparison of conventional and cooled radiofrequency treatment of the genicular nerves versus sham procedure for patients with chronic knee pain: protocol for a multicentre, double-blind, randomised controlled trial (COGENIUS)
por: Vanneste, Thibaut, et al.
Publicado: (2023)

Can open label placebos improve pain and gluten tolerance via open label placebos in fibromyalgia patients? A study protocol for a randomised clinical trial in an outpatient centre
por: Paschke, Lena, et al.
Publicado: (2023)

Intra-articular bupivacaine after joint arthroplasty: a systematic review and meta-analysis of randomised placebo-controlled studies
por: Cui, Yang, et al.
Publicado: (2016)

Postoperative analgesic effects of the quadratus lumborum block III and transversalis fascia plane block in paediatric patients with developmental dysplasia of the hip undergoing open reduction surgeries: a double-blinded randomised controlled trial
por: Huang, Congcong, et al.
Publicado: (2021)

Diaphragm ultrasound to evaluate the antagonistic effect of sugammadex on rocuronium after liver surgery in patients with different liver Child-Pugh grades: study protocol for a prospective, double-blind, non-randomised controlled trial
por: Sun, Shujun, et al.
Publicado: (2022)

Analgesic efficacy and safety of ketamine after total knee or hip arthroplasty: a meta-analysis of randomised placebo-controlled studies
por: Xu, Bei, et al.
Publicado: (2019)

Ultrasound-guided anterior quadratus lumborum block at the L2 level for postsurgical analgesia in patients undergoing laparoscopic gynaecological surgery: a single-centre, randomised, double-blinded trial at a university-affiliated hospital in China
por: Huang, Lvdan, et al.
Publicado: (2023)

Efficacy of perioperative intravenous lidocaine infusion on postoperative pulmonary complications in patients undergoing video-assisted thoracoscopic lung resection surgery: protocol for a randomised controlled trial
por: Wang, Fei, et al.
Publicado: (2022)

Effects of hydromorphone-based intravenous patient-controlled analgesia with and without a low basal infusion on postoperative hypoxaemia: study protocol for a randomised controlled clinical trial
por: Ma, Yumei, et al.
Publicado: (2022)

POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery
por: Beloeil, Helene, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_o9cahiu1nv2qrsd692i1lcfeab