Sodium channel mutations (T929I and F1534S) found in pyrethroid-resistant strains of the cigarette beetle, Lasioderma serricorne (Coleoptera: Anobiidae)

RNA-seq data analysis of cigarette beetle (Lasioderma serricorne) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel c...

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Detalles Bibliográficos
Autores principales: Fukazawa, Naoto, Takahashi, Ryota, Matsuda, Hinako, Mikawa, Yuya, Suzuki, Toshiyuki, Suzuki, Tomohiro, Sonoda, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pesticide Science Society of Japan 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640701/
https://www.ncbi.nlm.nih.gov/pubmed/34908896
http://dx.doi.org/10.1584/jpestics.D21-033
Descripción
Sumario:RNA-seq data analysis of cigarette beetle (Lasioderma serricorne) strains having different sensitivities to pyrethroids identified sodium channel mutations in strains showing pyrethroid resistance: the T929I and F1534S mutations. These results suggest that reduced sensitivity of the sodium channel confers the pyrethroid resistance of L. serricorne. Results also showed that the F1534S mutation mostly occurred concurrently with the T929I mutation. The functional relation between both mutations for pyrethroid resistance is discussed.

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