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Amyloid β 42 fibril structure based on small-angle scattering

Amyloid fibrils are associated with a number of neurodegenerative diseases, including fibrils of amyloid β42 peptide (Aβ42) in Alzheimer’s disease. These fibrils are a source of toxicity to neuronal cells through surface-catalyzed generation of toxic oligomers. Detailed knowledge of the fibril struc...

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Detalles Bibliográficos
Autores principales: Lattanzi, Veronica, André, Ingemar, Gasser, Urs, Dubackic, Marija, Olsson, Ulf, Linse, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640717/
https://www.ncbi.nlm.nih.gov/pubmed/34815346
http://dx.doi.org/10.1073/pnas.2112783118