Cargando…
Amyloid β 42 fibril structure based on small-angle scattering
Amyloid fibrils are associated with a number of neurodegenerative diseases, including fibrils of amyloid β42 peptide (Aβ42) in Alzheimer’s disease. These fibrils are a source of toxicity to neuronal cells through surface-catalyzed generation of toxic oligomers. Detailed knowledge of the fibril struc...
Autores principales: | Lattanzi, Veronica, André, Ingemar, Gasser, Urs, Dubackic, Marija, Olsson, Ulf, Linse, Sara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640717/ https://www.ncbi.nlm.nih.gov/pubmed/34815346 http://dx.doi.org/10.1073/pnas.2112783118 |
Ejemplares similares
-
On the Cluster Formation of α-Synuclein Fibrils
por: Dubackic, Marija, et al.
Publicado: (2021) -
High
Resolution Structural Characterization of Aβ(42) Amyloid
Fibrils by Magic Angle Spinning NMR
por: Colvin, Michael T., et al.
Publicado: (2015) -
Direct observation of secondary nucleation along the fibril surface of the amyloid β 42 peptide
por: Thacker, Dev, et al.
Publicado: (2023) -
Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
por: Törnquist, Mattias, et al.
Publicado: (2020) -
Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation
por: Braun, Gabriel A., et al.
Publicado: (2022)