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Pregnancy and weaning regulate human maternal liver size and function

During pregnancy, the rodent liver undergoes hepatocyte proliferation and increases in size, followed by weaning-induced involution via hepatocyte cell death and stromal remodeling, creating a prometastatic niche. These data suggest a mechanism for increased liver metastasis in breast cancer patient...

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Detalles Bibliográficos
Autores principales: Q. Bartlett, Alexandra, Vesco, Kimberly K., Purnell, Jonathan Q., Francisco, Melanie, Goddard, Erica, Guan, Xiangnan, DeBarber, Andrea, Leo, Michael C., Baetscher, Eric, Rooney, William, Naugler, Willscott, Guimaraes, Alexander R., Catalano, Patrick, Xia, Zheng, Schedin, Pepper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640831/
https://www.ncbi.nlm.nih.gov/pubmed/34815335
http://dx.doi.org/10.1073/pnas.2107269118

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